Human health and host-associated microbiomes
The human body is comprised of more than one microbial cell for every human cell and these microbial cells, the human microbiome, are both taxonomically and physiologically diverse. This hidden majority of microbial cells and genomic information often plays an outsized role in human health impacting inflammation, immunity, and a vast array of acute and chronic human health issues. Considerable efforts are underway to map the diversity, metabolic potential, and ecological principles that define interactions within the human microbiome and between the microbiome and the human host to inform translational outcomes across the health sector.